Barely Significant
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Aging does not enhance experimental cigarette smoke-induced COPD in the mouse.

PLoS One · 2013 · PMC3732225 · PMID 23936505

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showed a trendno p-value reported
Gene expression studies using laser capture microdissected airways and parenchyma overall showed a trend to lower levels in older animals and a somewhat lesser response to cigarette smoke in both airways and parenchyma but the differences were usually not marked.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.