Immunostaining for ROCK1 expression in the myocardium and endothelium was not significantly different between diabetic and control animals although there was a notable trend towards an increase.
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Acute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculation.
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The sentences
This study also revealed a strong trend towards an increased incidence of segmental constrictions in diabetic animals when there is a deficit in vasodilator production.