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Bioassay-guided evaluation of Dioscorea villosa - an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach.

BMC Complement Altern Med · 2013 · PMC3734200 · PMID 23889998

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a strong trendno p-value reported
There is a strong trend in the use of natural substances with therapeutic activity, particularly in diseases in which clinically used synthetic drugs, such as analgesic, anti-inflammatory and hormonal drugs have several complications and side effects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.