Barely Significant
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HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation.

PLoS One · 2013 · PMC3738515 · PMID 23951115

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quite significantno p-value reported
This implies that the effect of DO can be quite significant and dominant over the effects of DM.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.