Heterogeneity in effect sizes between class I/II and class III obesity was statistically significant only for FTO rs9939609 ( P het = 0.031) and borderline significant for MC4R rs17782313 ( P het = 0.050).
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Contribution of common genetic variants to obesity and obesity-related traits in mexican children and adults.
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The sentences
It is noteworthy that, although FTO was most significantly associated with obesity in the case-control study, its association with BMI did not reach statistical significance in children, adults or in the combined analyses ( P add = 0.125, 0.392 and 0.085, respectively).