Barely Significant
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Prognostic significance of ESR1 amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 polymorphisms in breast cancer patients.

PLoS One · 2013 · PMC3738574 · PMID 23951298

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showed a trendP =0.08so close (0.05 < p ≤ 0.1)
Patients with ESR1 PvuII wt/wt genotype and at least one UGT2B15 wt allele had a worse DFS ( P =0.03) and showed a trend towards decreased Os ( P =0.08) in comparison to patients with ESR1 PvuII wt/vt or vt/vt genotype and UGT2B15 *2/*2 genotype.

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