A meta-analysis of all five samples resulted in a pooled association estimate of 0.42 ± 0.26 years earlier age at onset of schizophrenia per T-allele (mean ± SE), which did not reach statistical significance ( P = 0.17).
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Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population.
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0.1700
0.1700