The major brain endocannabinoid 2-AG controls neuropathic pain and mechanical hyperalgesia in patients with neuromyelitis optica.

PLoS One · 2013 · PMC3739748 · PMID 23951176

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0.0700

closest p · 1.4× alpha

0.0700

boldest claim

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a strong trendp = 0.07so close (0.05 < p ≤ 0.1)

In addition, pain sensitivity for pinprick stimuli (MPS) was significantly reduced in the hand of NMO patients (p<0.05), accompanied by a strong trend towards MPS reduction in the feet (p = 0.07; Table 4 ).

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