A study of financial incentives to reduce plasma HIV RNA among patients in care.

There was no evidence of “adherence fatigue”, with the proportion of undetectable viral loads rising throughout the intervention period (64 %, first quarter; 66 %, second quarter; 69 %, third quarter; and 78 %, fourth quarter). AUC/day viral load decreased from 2.2 (95 % confidence interval, 1.7–2.6) to 1.9 (1.8–2.0) for intent-to-treat ( t = −1.3, p = 0.19) and from 2.1 (1.7–2.6) to 1.9 (1.8–1.9) in the as-treated ( t = −1.2, p = 0.23), but did not reach statistical significance with the number of patients available.

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