Sexually dimorphic, developmental, and chronobiological behavioral profiles of a mouse mania model.

We found a highly significant strain effect ( F 1, 60 = 96.28, p = 4.4×10 −14 , η p 2 = 0.616), a significant sex effect ( F 1, 60 = 11.44, p = 0.0013, η p 2 = 0.160), and no significant interaction effect ( F 1, 60 = 0.04, p = 0.84, η p 2 = 0.001) using a two-way ANOVA on transformed in-cage activity.

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We found a highly significant strain effect ( F 1, 56 = 102.07, p = 3.2×10 −14 , η p 2 = 0.646), no significant effect of week studied ( F 3, 56 = 1.72, p = 0.17, η p 2 = 0.084), and a modestly significant interaction effect ( F 3, 56 = 2.96, p = 0.040, η p 2 = 0.137) using a two-way ANOVA on transformed in-cage activity data.

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We checked the nominal significance of each of these tests using two-tailed t-tests, and each was nominally significant at p <0.05.

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