Long-term exercise and risk of metabolic and cardiac diseases: the erlangen fitness and prevention study.

(aerobic exercise: 179 min/week at 40%–55% VO 2 peak versus 114 min at 65%–80% VO 2 peak versus 175 min at 65%–80% VO 2 peak for 8 months) widely differ from the present exercise protocol, in line with our data, 3 out of 4 exercise protocols/study arms resulted in significant positive MetS Z -score changes among the EG and significant differences compared with a nontraining control group (with slight, nonsignificant changes) while results of one study arm (114 min at 65%–80% VO 2 peak; [ 9 ]) did not reach statistical significance.

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Although the ITT-analysis presented in Table 3 resulted in slightly lower effect sizes, all the differences remained highly significant.

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