Association of genetic variation in adaptor protein APPL1/APPL2 loci with non-alcoholic fatty liver disease.

PLoS One · 2013 · PMC3747137 · PMID 23977033

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did not reach statistical significanceno p-value reported

Comparing the different grading of hepatic steatosis among the three genotype groups there was an increased frequency of severe steatosis in NAFLD individuals with APPL1-CC genotype; a trend for individuals with APPL2 AA genotype to have an higher frequency of severe steatosis was also found; the differences however did not reach statistical significance ( Figure 1 ).

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