an increasing trendP = 0.037
Among all microvascular complications, there was an increasing trend in the proportions developing impaired eGFR (3.6 vs. 3.9 vs. 6.6%, trend P = 0.037) and ESRD (0 vs. 1.5 vs. 2.3%, trend P = 0.036) among those with 0, 1, or 2 copies of the HP 2 allele, respectively.