Very low-calorie diet mimics the early beneficial effect of Roux-en-Y gastric bypass on insulin sensitivity and β-cell Function in type 2 diabetic patients.

There were significant increases in adiponectin and GLP-1 in the RYGB group, and the difference in change from baseline between groups approached significance ( Table 3 ) ( P = 0.05 and 0.10 for change in adiponectin and GLP-1, respectively).

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