showed a trendP = 0.08
In type 2 diabetic patients treated with a GLP-1 RA ( n = 173), none of the SNPs showed a significant association; although rs4148941, located in CHST3 , showed a trend toward lower treatment response in C-allele carriers (0.24 ± 0.13% [2.6 ± 1.4 mmol/mol]; P = 0.08) ( Table 2 and Supplementary Tables 5 and 6 ).