Barely Significant
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The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.

PLoS Genet · 2013 · PMC3750021 · PMID 23990795

1
hedged sentence
0.2700
closest p · 5.4× alpha
0.2700
boldest claim

The sentences

did not reach statistical significancep = 0.27not close (p > 0.1)
However, it did not reach statistical significance in individuals with Aβ deposition (p = 0.27, OR = 3.4, 95%CI = 0.38–30.7).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.