Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency.

WAS KO mice also mounted CD8 + T-cell responses specific for the immunodominant epitope of the LCMV nucleoprotein (NP396), but although reduced compared with values seen in C57BL/6 mice, this did not reach statistical significance (see Fig E1 in this article's Online Repository at www.jacionline.org ).

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