showed a trendp = 0.09
Males exhibited a significant negative correlation between IL-1β and contextual fear memory [ r (26) = –0.33, p < 0.05], such that higher levels of proinflammatory IL-1β were associated with decreased freezing in the fear context, whereas females showed a trend for a positive correlation [ r (27) = 0.27, p = 0.09] ( Figure 5D ).