Barely Significant
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Translational HIV-1 research: from routine diagnostics to new virology insights in Amsterdam, the Netherlands during 1983-2013.

Retrovirology · 2013 · PMC3765835 · PMID 23985078

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a clear trendno p-value reported
We observed a clear trend of increasing fitness over time in the HIV-1 epidemic of Amsterdam.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.