Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosis.

PLoS One · 2013 · PMC3772944 · PMID 24058572

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failed to reach statistical significanceP=0.08so close (0.05 < p ≤ 0.1)

Relationship between selected nuclear receptors mRNA, CYP3A4 mRNA and CYP3A activity The negative correlation between CYP3A4 mRNA and hepatic CYP3A activity in cirrhotic liver samples failed to reach statistical significance (r = -0.43, P=0.08).

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