A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes.

J Biol Chem · 2013 · PMC3774380 · PMID 23744070

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showed a trendno p-value reported

Mice injected with des-His 1 -Glu 9 -GCG at both doses (2 and 4 mg/kg) showed a trend toward the attenuated increase in blood glucose as compared with vehicle-treated animals ( Fig. 9 , A and B ).

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