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Inflammatory mediators influence the expression of nociceptin and its receptor in human whole blood cultures.

PLoS One · 2013 · PMC3774641 · PMID 24066107

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The combination led to a stronger recovery of NOP expression when compared to the group treated with anti-IL-1β only (p = 0.0075), while the difference did not reach statistical significance when compared to the group with anti-TNF-α only.

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