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Popeye domain containing 1 (Popdc1/Bves) is a caveolae-associated protein involved in ischemia tolerance.

PLoS One · 2013 · PMC3774711 · PMID 24066022

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The necrotic damage in hearts of heterozygotes was larger than in WT and smaller than in homozygotes, yet each of the comparisons did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.