(R)-[(11)C]verapamil is selectively transported by murine and human P-glycoprotein at the blood-brain barrier, and not by MRP1 and BCRP.

Nucl Med Biol · 2013 · PMC3775124 · PMID 23845421

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did not reach statistical significanceno p-value reported

In Mdr1a/b (−/−) Bcrp1 (−/−) mice, K b,brain was by about 30% decreased relative to scan 1, but this did not reach statistical significance.

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