Single nucleotide polymorphisms within LIPA (Lysosomal Acid Lipase A) gene are associated with susceptibility to premature coronary artery disease. a replication in the genetic of atherosclerotic disease (GEA) Mexican study.

PLoS One · 2013 · PMC3775807 · PMID 24069331

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did not reach statistical significanceno p-value reported

[ 11 ] reported that elevated LIPA expression was significantly associated with lower HDL-cholesterol levels and impaired endothelial function measured by flow-mediated vasodilatation, whereas associations with higher levels of LDL-cholesterol and triglycerides did not reach statistical significance.

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