Impact of body mass index on estradiol depletion by aromatase inhibitors in postmenopausal women with early breast cancer.

After 3 months of treatment with an AI, a moderate, barely significant correlation between BMI and estradiol serum level could be detected ( r =0.35, P =0.05).

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The observation concerning a difference in depleted estradiol levels according to BMI was subtle and did not reach statistical significance due to a limited sample of patients and statistical power.

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