Role of colesevelam in combination lipid-lowering therapy.

Similarly, in the lovastatin study, increases in apo A-I were significant with colesevelam alone (+8 %; p < 0.0001), lovastatin alone (+5 %; p < 0.05), and colesevelam plus lovastatin dosed together (+5 %; p < 0.05), but did not reach statistical significance with colesevelam plus lovastatin dosed apart (+4 %) [ 40 ].

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