In addition, a gene-based analysis interrogating for association with schizophrenia based on the meta-analytic p values obtained by the largest schizophrenia genome-wide association study to date ( Ripke et al., 2011 ) (9,394 cases and 12,462 controls) revealed that 8 out of 36 tested autosomal genes of the CYFIP1 interactome had a nominally significant p value (<0.05) for association with schizophrenia ( Tables S4–S6 ).
← all excerpts
CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation.
1
—
—