Amyloid beta inhibits olfactory bulb activity and the ability to smell.

Bath application of 3 nM Aβ induces reduction in OB network activity ( Figure 3F ) to 65.2 ± 4.9% of control; this reduction did not reach statistical significance when tested by Dunn’s test (after a Friedman test), but it was significantly different from the control when evaluated by the Wilcoxon test (p < 0.05).

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