Electron microscopy revealed a highly significant increase in intermyofibrillar mitochondria (+55%) and augmented coupling (+12%) between Ca 2+ release units of the SR and mitochondria in dCASQ-null vs.
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Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.
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The sentences
The type-dependent difference in the rate constant k 3 which is significant when the values obtained at all stimulation rates are pooled together (see above), is visible as a trend but did not reach statistical significance in the results using 1 Hz stimulation only.