Exposure values of imatinib and CGP74588 on C1D1 (AUC 0-inf ) and C2D1 (AUC 0–24 h because imatinib is at steady state) appeared to increase, but these effects did not reach statistical significance ( P =0.063), as shown in Figures 2A and B and Table 4 .
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A phase 1 trial of imatinib, bevacizumab, and metronomic cyclophosphamide in advanced colorectal cancer.
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0.0630
0.0630