17 Of note, a Phase III trial testing topotecan treatment versus PLD treatment showed a trend toward a higher RR in the platinum-resistant OC patient subset treated with PLD, although there was no improvement of PFS or OS. 18 , 19 Gemcitabine Gemcitabine could be considered an alternative to PLD for treatment of platinum-resistant OC.
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Patient selection and targeted treatment in the management of platinum-resistant ovarian cancer.
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