An association study of TOLL and CARD with leprosy susceptibility in Chinese population.

Hum Mol Genet · 2013 · PMC3792694 · PMID 23784377

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0995

boldest claim

The sentences

highly significantP = 1.27 × 10 −7actually significant

The association at rs2735591 is highly significant in the combined validation samples ( P = 1.27 × 10 −7 , OR = 1.27), even after correction for all the 4363 SNPs tested in the current study ( P corrected = 5.54 × 10 −4 ) and surpassed the genome-wide significance threshold ( P = 1.03 × 10 −9 , OR = 1.24) in the combined GWAS and two independent validation series, consisting of a total of 3148 cases and 7843 controls (Table 2 ).

also in 132,142 other papers

did not reach statistical significanceP = 0.0995so close (0.05 < p ≤ 0.1)

Among these 141 unique genes, 2 are TLR / CARD genes, which comprises 2.5% of the total TLR / CARD genes within the genome, but Pearson's chi-square test with Yates’ continuity correction (as implemented in R statistical package under the function chisq.test) did not reach statistical significance and only showed suggestive evidence of enrichment (one-sided P = 0.0995).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.