Probing the interaction of a therapeutic flavonoid, pinostrobin with human serum albumin: multiple spectroscopic and molecular modeling investigations.

A clear trend of decreasing fluorescence intensity accompanied by blue shift for both peaks ‘1’ and ‘2’ of HSA was noticed with increasing PS/HSA molar ratios ( Table 2 ); suggestive of significant conformational alteration in HSA involving both secondary and tertiary structures upon specific interaction with PS.

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