Barely Significant
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The fold variant BM4 is beneficial in a therapeutic Bet v 1 mouse model.

Biomed Res Int · 2013 · PMC3794650 · PMID 24175303

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a clear trendno p-value reported
Treatment with BM4 Was Able to Shift an Allergic Immune Response Analyses of splenocyte supernatants of either actively or sham treated animals, which were re-stimulated with Bet v 1, revealed a clear trend showing that BM4 treatment led to suppression of the TH2 cytokines IL-5 and IL-13 accompanied by an upregulation of IFN- γ and IL-10.

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