Prevalence of the prescription of potentially interacting drugs.

PLoS One · 2013 · PMC3795676 · PMID 24147143

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a clear trendno p-value reported

Generally, ages ≥50 years were associated with an increased risk; a clear trend was observed in 19 cohorts, with the strongest evidence in the levothyroxine cohort for warfarin concomitance (aORs 2.75 [95% CI 2.10-3.61], 6.99 [95% CI 5.38-9.07], and 11.26 [95% CI 8.66-14.63] in the three age groups, respectively, vs the <50 years class).

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