An open-label study of algorithm-based treatment versus treatment-as-usual for patients with schizophrenia.

Chlorpromazine-equivalent antipsychotic dosage (mean ± SD) was 386.6 ± 258.5 mg for the ALGO group and 540.4 ± 362.5 mg for the TAU group at 24 weeks, which failed to reach statistical significance likely due to the limited number of patients, a wider variability in dosage requirements, and more attritions at later treatment weeks ( Figure S2 ).

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