77 Polymorphisms in BDNF , DRD4 , DAOA , and TPH1 (tryptophan hydroxylase 1) were found to be nominally significant; however, none of these findings was significant after correction for multiple testing.
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Evidence for single nucleotide polymorphisms and their association with bipolar disorder.
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88 Another GWAS performed on neurocognition in 157 BD patients and 353 controls 89 identified three intronic SNPs in the PTPRO (protein tyrosine phosphatase receptor type O) gene associated with learning and memory (rs17222089, rs11056571, and rs2300290) and rs719714 near WDR72 (WD repeat domain 72) associated with executive functioning as well as highly significant interaction between FOXQ1 (forkhead box Q1) and SUMO1P1 (SUMO1 pseudogene 1) SNPs for psychomotor speed.