Influence of Atg5 mutation in SLE depends on functional IL-10 genotype.

PLoS One · 2013 · PMC3799636 · PMID 24205307

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a clear trendno p-value reported

According to previous data ( Figure 1 ), Atg5 rs573775 significantly influences, but in an opposite way, IFNα and IL-10 levels, whereas a clear trend was detected for TNFα.

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a slight trendno p-value reported

In addition, a slight trend towards lower production of TNFα, a cytokine positively correlated with IFNα in SLE patients was also observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.