Barely Significant
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Coagulation activation in children with sickle cell disease is associated with cerebral small vessel vasculopathy.

PLoS One · 2013 · PMC3808283 · PMID 24205317

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Patients with cerebral silent infarcts presented significantly lower mean t-PA:Ag and ADAMTS13:Ag levels and higher D-dimer, F1+2 and TAT levels, although these latter did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.