Association of maternal CNVs in GSTT1/GSTT2 with smoking, preterm delivery, and low birth weight.

The GSTT2 a deletion was associated with reduced birth weight in full term controls with borderline significance when smoking status was not considered (Table 3B ; −65.3 g, p = 0.06), but was not associated with preterm birth or birth before 35 weeks (Table 2 ).

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None of the interactions between these five CNVs with smoking were near statistical significance after evaluating a model of birthweight regressed on maternal BMI, infant sex, genotype, and genotype x smoking status (Table 2 , P int ).

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