Topoisomerase II regulates yeast genes with singular chromatin architectures.

Nucleic Acids Res · 2013 · PMC3814376 · PMID 23935120

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a strong trendno p-value reported

The upregulated group of genes exhibits instead a strong trend to be hypo-methylated and hypo-acetylated, at both their promoter and ORF regions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.