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The use of central nervous system active drugs during pregnancy.

Pharmaceuticals (Basel) · 2013 · PMC3817603 · PMID 24275849

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When individual anticonvulsants were studied, valproic acid was associated with an increased risk for preterm birth (OR = 1.61, 95% CI 1.16–2.98) while the ORs for carbamazepine (1.22, 95% CI 0.95–2.00) and lamotrigine (OR 1.21, 95% CI 0.83–1.77) were lower and did not reach statistical significance.

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