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PGE 2 desensitizes β -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4.

Mediators Inflamm · 2013 · PMC3817676 · PMID 24227907

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By contrast, there was a slight reduction of contraction in the presence of cilomilast that did not reach statistical significance ( Figure 3(b) ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.