All haplotype groups tested showed highly significant associations with CD (including omnibus P -values as low as 6.1×10 −18 ).
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Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2.
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The sentences
All tests were two-tailed and P- values <0.05 were considered nominally significant.