Barely Significant
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PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort.

PLoS One · 2013 · PMC3819371 · PMID 24223163

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Although the odds ratio estimate was consistent with that in the discovery sample, association did not reach statistical significance in the replication sample (OR = 1.18 vs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.