a strong trendP = 0.051
Recent studies with prehospital administration of high-dose bolus tirofiban in the ambulance in addition to aspirin, heparin, and clopidogrel showed a significantly lower residual ST-segment deviation versus placebo [ 94 ], which resulted in a strong trend for decreased mortality at 30 days (2.2% versus 4.1%, P = 0.051) and 1 year (3.7% versus 5.8%, P = 0.08) as well as a significant reduction in major adverse cardiac events at 30 days compared with placebo (5.8% versus 8.6%, P = 0.043) [ 95 ]. 8.