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Heart rate reduction for 36 months with ivabradine reduces left ventricular mass in cardiac allograft recipients: a long-term follow-up study.

Drug Des Devel Ther · 2013 · PMC3821694 · PMID 24235815

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7 , 8 A reduction in mean heart rate at rest was also observed in the control group after 36 months, but this did not reach statistical significance, which might possibly be attributable to reinnervation processes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.