RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism.

J Cell Mol Med · 2009 · PMC3822518 · PMID 19374686

Europe PMC DOI

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only marginally significantno p-value reported

It might be speculated that the higher CSF levels of 24S-hydroxycholesterol in non-demented persons who are homozygote carriers of the RXRA risk genotype might induce an increased synthesis of lathosterol, although the changes in the 24S-hydroxycholesterol levels were only marginally significant in these probands.

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