Activation of neurokinin-1 receptors up-regulates substance P and neurokinin-1 receptor expression in murine pancreatic acinar cells.

J Cell Mol Med · 2012 · PMC3823226 · PMID 22040127

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0.1500

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showed a trendP < 0.15not close (p > 0.1)

At a low concentration of 0.2 μM, CP96,345 showed a trend of inhibition (0.05 < P < 0.15) but at higher concentrations (5 μM), it completely abolished SP-induced up-regulation of PPTA/NK1R mRNA expression ( Fig. 2A and B).

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